Publications

Direct Detection and Quantification of Bacterial Genes Associated with Inflammation in DNA Isolated from Stool

Gómez-Moreno R, Robledo IE, Baerga-Ortiz A. Direct Detection and Quantification of Bacterial Genes Associated with Inflammation in DNA Isolated from Stool. Adv Microbiol. 2014 Nov;4(15):1065-1075.

  • PubMed PMID: 25635239;
  • PubMed Central PMCID: PMC4307837.

Real-Time Detection of Telomerase Activity in Cancer Cells using a Label-Free Electrochemical Impedimetric Biosensing Microchip.

Cunci L, Vargas MM, Cunci R, Gomez-Moreno R, Perez I, Baerga-Ortiz A, Gonzalez CI, Cabrera CR. Real-Time Detection of Telomerase Activity in Cancer Cells using a Label-Free Electrochemical Impedimetric Biosensing Microchip. RSC Adv. 2014 Oct 15;4(94):52357-52365.

  • PubMed PMID: 25598969;
  • PubMed Central PMCID: PMC4295792.

Expression of dehydratase domains from a polyunsaturated fatty acid synthase increases the production of fatty acids in Escherichia coli.

Oyola-Robles D, Rullán-Lind C, Carballeira NM, Baerga-Ortiz A. Expression of dehydratase domains from a polyunsaturated fatty acid synthase increases the production of fatty acids in Escherichia coli. Enzyme Microb Technol. 2014 Feb 5;55:133-9. doi: 10.1016/j.enzmictec.2013.10.010. Epub 2013 Nov 8.

  • PubMed PMID: 24411456;
  • PubMed Central PMCID: PMC3894691.

Identification of novel protein domains required for the expression of an active dehydratase fragment from a polyunsaturated fatty acid synthase.

Oyola-Robles D, Gay DC, Trujillo U, Sánchez-Parés JM, Bermúdez ML, Rivera-Díaz M, Carballeira NM, Baerga-Ortiz A. Identification of novel protein domains required for the expression of an active dehydratase fragment from a polyunsaturated fatty acid synthase. Protein Sci. 2013 Jul;22(7):954-63. doi:10.1002/pro.2278. Epub 2013 Jun 6.

  • PubMed PMID: 23696301;
  • PubMed Central PMCID:PMC3719089.

Solution structure of the tandem acyl carrier protein domains from a polyunsaturated fatty acid synthase reveals beads-on-a-string configuration.

Trujillo U, Vázquez-Rosa E, Oyola-Robles D, Stagg LJ, Vassallo DA, Vega IE, Arold ST, Baerga-Ortiz A. Solution structure of the tandem acyl carrier protein domains from a polyunsaturated fatty acid synthase reveals beads-on-a-string configuration. PLoS One. 2013;8(2):e57859. doi: 10.1371/journal.pone.0057859.Epub 2013 Feb 28.

  • PubMed PMID: 23469090;
  • PubMed Central PMCID: PMC3585217.

Structure, activity, and substrate selectivity of the Orf6 thioesterase from Photobacterium profundum.

Rodríguez-Guilbe M, Oyola-Robles D, Schreiter ER, Baerga-Ortiz A. Structure, activity, and substrate selectivity of the Orf6 thioesterase from Photobacterium profundum. J Biol Chem. 2013 Apr 12;288(15):10841-8. doi:10.1074/jbc.M112.446765. Epub 2013 Feb 21.

  • PubMed PMID: 23430744;
  • PubMed Central PMCID: PMC3624464.

Structures, semisyntheses, and absolute configurations of the antiplasmodial α-substituted β-lactam monamphilectines B and C from the sponge Svenzea flava.

Avilés E, Prudhomme J, Le Roch KG, Rodríguez AD. Structures, semisyntheses, and absolute configurations of the antiplasmodial α-substituted β-lactam monamphilectines B and C from the sponge Svenzea flava. Tetrahedron. 2015 Jan 21;71(3):487-494.

  • PubMed PMID: 26494928;
  • PubMed Central PMCID: PMC4610402.

Synthesis and preliminary biological evaluation of a small library of hybrid compounds based on Ugi isocyanide multicomponent reactions with a marine natural product scaffold.

Avilés E, Prudhomme J, Le Roch KG, Franzblau SG, Chandrasena K, Mayer AM, Rodríguez AD. Synthesis and preliminary biological evaluation of a small library of hybrid compounds based on Ugi isocyanide multicomponent reactions with a marine natural product scaffold. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5339-43. doi: 10.1016/j.bmcl.2015.09.033. Epub 2015 Sep 15.

  • PubMed PMID: 26421992.

Euryjanicins E-G, poly-phenylalanine and poly-proline cyclic heptapeptides from the Caribbean sponge Prosuberites laughlini. Tetrahedron.

Avilés E, Rodríguez AD. Euryjanicins E-G, poly-phenylalanine and poly-proline cyclic heptapeptides from the Caribbean sponge Prosuberites laughlini. Tetrahedron. 2013 Dec 23;69(51):10797-10804. Epub 2013 Nov 5.

  • PubMed PMID: 26491207;
  • PubMed Central PMCID: PMC4610400.

Dactyloditerpenol acetate, a new prenylbisabolane-type diterpene from Aplysia dactylomela with significant in vitro anti-neuroinflammatory activity.

Jiménez-Romero C, Mayer AM, Rodríguez AD. Dactyloditerpenol acetate, a new prenylbisabolane-type diterpene from Aplysia dactylomela with significant in vitro anti-neuroinflammatory activity.

  • PubMed PMID:24279991
  • PubMed Central PMCID: PMC4249741.

Two rare-class tricyclic diterpenes with antitubercular activity from the Caribbean sponge Svenzea flava. Application of vibrational circular dichroism spectroscopy for determining absolute configuration.

Avilés E, Rodríguez AD, Vicente J. Two rare-class tricyclic diterpenes with antitubercular activity from the Caribbean sponge Svenzea flava. Application of vibrational circular dichroism spectroscopy for determining absolute configuration.

  • PubMed PMID: 24138557
  • PubMed Central PMCID: PMC4610370.

Simultaneous structure-activity studies and arming of natural products by C-H amination reveal cellular targets of eupalmerin acetate.

Li J, Cisar JS, Zhou CY, Vera B, Williams H, Rodríguez AD, Cravatt BF, Romo D. Simultaneous structure-activity studies and arming of natural products by C-H amination reveal cellular targets of eupalmerin acetate.

  • PubMed PMID: 23695633
  • PubMed Central PMCID: PMC4041531.

3β-Chloro-N-methoxy-N-methyl-cholest-5-ene-24-carboxamide.

González K, Nieves K, Rodríguez AD. 3β-Chloro-N-methoxy-N-methyl-cholest-5-ene-24-carboxamide.

  • PubMed PMID: 23476280
  • PubMed Central PMCID: PMC3589044

Draft genome sequences of five novel polyketide synthetase-containing mouse Escherichia coli strains.

Mannion A, Shen Z, Feng Y, Garcia A, Fox JG. Draft genome sequences of five novel polyketide synthetase-containing mouse Escherichia coli strains. Genome Announcements 4(5): e01082-16, 2016.

Cytotoxic Escherichia coli strains encoding colibactin colonize laboratory mice.

García A, Mannion A, Feng Y, Madden CM, Bakthavatchalu V, Shen Z, Ge Z, Fox JG. Cytotoxic Escherichia coli strains encoding colibactin colonize laboratory mice. Microbes and Infection July 30, 2016 (Epub ahead of print).

Generating chimeric mice by using embryos from nonsuperovulated BALB/c mice compared with superovulated BALB/c and Albino C57BL/6 mice.

Esmail MY, Qi P, Connor AB, Fox JG, García A. Generating chimeric mice by using embryos from nonsuperovulated BALB/c mice compared with superovulated BALB/c and Albino C57BL/6 mice. Journal of the American Association for Laboratory Animal Science 55(4): 400-405, 2016.

Chapter 10: Biology and diseases of rabbits. In: Laboratory Animal Medicine, 3rd Edition.

Nowland MH, Brammer DW, Garcia A, Rush HG. Chapter 10: Biology and diseases of rabbits. In: Laboratory Animal Medicine, 3rd Edition. Fox JG, Anderson LC, Otto G, Pritchett-Corning KR, Whary MT. Academic Press, Elsevier, 2015.

Helicobacter hepaticus infection promotes hepatitis and preneoplastic foci in farsenoid X receptor (FXR) deficient mice.

Swennes AG, Sheh A, Parry NM, Muthupalani S, Lertpiriyapong K, García A, Fox JG. Helicobacter hepaticus infection promotes hepatitis and preneoplastic foci in farsenoid X receptor (FXR) deficient mice. PloS One 9(9): e106764, 2014.

Administration of luteinizing hormone releasing hormone agonist for synchronization of estrus and generation of pseudopregnancy for embryo
transfer in rats.

Borjeson TM, Pang J, Fox JG, García A. Administration of luteinizing hormone releasing hormone agonist for synchronization of estrus and generation of pseudopregnancy for embryotransfer in rats. Journal of the American Association for Laboratory Animal Science 53(3): 232-237, 2014.

Laser- assisted in vitro fertilization facilitates fertilization of vitrified-warmed C57BL/6 mouse oocytes with fresh and frozen-thawed spermatozoa, producing live pups.

Woods SE, Qi P, Rosalia E, Chavarria T, Discua A, Mkandawire J, Fox JG, García A. Laser- assisted in vitro fertilization facilitates fertilization of vitrified-warmed C57BL/6 mouse oocytes with fresh and frozen-thawed spermatozoa, producing live pups. PLoS One 8(3): e91892, 2014.

Helicobacter pylori infection does not promote hepatocellular cancer in a transgenic mouse model of hepatitis C virus pathogenesis.

García A, Feng Y, Parry NM, McCabe A, Mobley MW, Lertpiriyapong K, Whary MT, Fox JG. Helicobacter pylori infection does not promote hepatocellular cancer in a transgenic mouse model of hepatitis C virus pathogenesis. Gut Microbes 4(6): 577-590, 2013.

Hepatobiliary Disease (Ferrets). In: Clinical Veterinary Advisor Birds and Exotic Pets.

García A. Hepatobiliary Disease (Ferrets). In: Clinical Veterinary Advisor Birds and Exotic Pets. Mayer J, Donnelly TM (Editors-In-Chief). Elsevier. Pages 461-462, 2013.

Enzootic enteropathogenic Escherichia coli infection in laboratory rabbits.

Swennes AG, Buckley EM, Parry NM, Madden CM, García A, Morgan PB, Astrofsky KM, Fox JG. Enzootic enteropathogenic Escherichia coli infection in laboratory rabbits. Journal of Clinical Microbiology 50(7): 2353-2358, 2012.

Differential virulence of clinical and bovine-biased enterohemorrhagic Escherichia coli O157:H7 genotypes in piglet and Dutch belted rabbit models.

Shringi S, García A, Lahmers KK, Potter KA, Muthupalani S, Swennes AG, Hovde CJ, Call DR, Fox JG, Besser TE. Differential virulence of clinical and bovine-biased enterohemorrhagic Escherichia coli O157:H7 genotypes in piglet and Dutch belted rabbit models. Infection and Immunity 80(1): 369- 380, 2012.

Catalytic effect of ultrananocrystalline Fe3O4 on algal bio-crude production via HTL process.

Rojas-Pérez A, Diaz-Diestra D, Frias-Flores CB, Beltran-Huarac J, Das KC, Weiner BR, Morell G, Díaz-Vázquez LM. Catalytic effect of ultrananocrystalline Fe3O4 on algal bio-crude production via HTL process.

  • PubMed PMID: 26465090.

Ultrananocrystalline diamond-decorated silicon nanowire field emitters.

Palomino J, Varshney D, Resto O, Weiner BR, Morell G. Ultrananocrystalline diamond-decorated silicon nanowire field emitters.

  • PubMed PMID: 25046006.

Single-crystal γ-MnS nanowires conformally coated with carbon.

Beltran-Huarac J, Resto O, Carpena-Nuñez J, Jadwisienczak WM, Fonseca LF, Weiner BR, Morell G. Single-crystal γ-MnS nanowires conformally coated with carbon. ACS Appl Mater Interfaces.

  • PubMed PMID: 24392737.

Single-step route to diamond-nanotube composite.

Varshney D, Ahmadi M, Guinel MJ, Weiner BR, Morell G. Single-step route to diamond-nanotube composite.

  • PubMed PMID: 23013660;
  • PubMed Central PMCID: PMC3519742.

Surface analysis and electrochemistry of a robustcarbon-nanofiber-based electrode platform H2O2 sensor

Suazo-Dávila, D.; Rivera-Meléndez, J.; Koehne, J. E.; Meyyappan, M.; Cabrera, C. R.

 

  • DOI:10.1016/j.apsusc.2016.05.027

Cerium oxide as a promoter for the electro-oxidation reaction of ethanol: in situ XAFS characterization of the Pt nanoparticles supported on CeO(2) nanoparticles and nanorods.

Corchado-García J, Betancourt LE, Vélez CA, Senanayake SD, Stacchiola D, Sasaki K, Guinel MJ, Zhou Y, Cheung CL, Cabrera CR. Cerium oxide as a promoter for the electro-oxidation reaction of ethanol: in situ XAFS characterization of the Pt nanoparticles supported on CeO(2) nanoparticles and nanorods.

  • PubMed PMID: 26580293.

Graphene oxide as a protein matrix: influence on protein biophysical properties.

Hernández-Cancel G, Suazo-Dávila D, Ojeda-Cruzado AJ, García-Torres D, Cabrera CR, Griebenow K. Graphene oxide as a protein matrix: influence on protein biophysical properties. J Nanobiotechnology.

  • PubMed Central PMCID:PMC4617716.

Implementation of Various Modalities of the Optical-Optical Double Resonance Techniques To Simplify the Interpretation of the Spectra of Highly Excited States of Nitric Oxide.

Lin YG, Colón-García JE, Cabrera CR, Quiñones E. Implementation of Various Modalities of the Optical-Optical Double Resonance Techniques To Simplify the Interpretation of the Spectra of Highly Excited States of Nitric Oxide.

  • PubMed PMID: 26166549.

Assembly of a Cost-Effective Anode Using Palladium Nanoparticles for Alkaline Fuel Cell Applications.

Feliciano-Ramos I, Casañas-Montes B, García-Maldonado MM, Menéndez CL, Mayol AR, Díaz-Vázquez LM, Cabrera CR. Assembly of a Cost-Effective Anode Using Palladium Nanoparticles for Alkaline Fuel Cell Applications.

  • PubMed PMID: 25691801
  • PubMed Central PMCID: PMC4325606.

Real-Time Detection of Telomerase Activity in Cancer Cells using a Label-Free Electrochemical Impedimetric Biosensing Microchip

Cunci L, Vargas MM, Cunci R, Gomez-Moreno R, Perez I, Baerga-Ortiz A, Gonzalez CI, Cabrera CR. Real-Time Detection of Telomerase Activity in Cancer Cells using a Label-Free Electrochemical Impedimetric Biosensing Microchip. RSC Adv. 2014 Oct 15;4(94):52357-52365.

  • PubMed PMID: 25598969
  • PubMed Central PMCID: PMC4295792.

Screening for liver cancer during transplant waiting list: a multicenter study from South America.

Piñero F, Marciano S, Anders M, Orozco F, Zerega A, Cabrera CR, Baña MT, Gil O, Andriani O, de Santibañes E, McCormack L, Gadano A, Silva M. Screening for liver cancer during transplant waiting list: a multicenter study from South America.

  • PubMed PMID: 25563142.

Synthesis and electrocatalytic properties of H2SO4 -induced (100) Pt nanoparticles prepared in water-in-oil microemulsion.

Martínez-Rodríguez RA, Vidal-Iglesias FJ, Solla-Gullón J, Cabrera CR, Feliu JM. Synthesis and electrocatalytic properties of H2SO4 -induced (100) Pt nanoparticles prepared in water-in-oil microemulsion.

  • PubMed PMID: 24648299.

Influence of nanostructured ceria support on platinum nanoparticles for alkaline methanol Electrooxidation

Zhou, Y.; Menéndez; C.L.; Guinel, M.J.; Needels; E.C.; González-González, I.; Jackson, D.; Lawrence, N.J.; Cabrera, C.R.; Ph.D.; Cheung, C.L.

 

  • DOI: 10.1039/C3RA45829F

Evaluation of an externally interfaced forward osmosis and bio-electrochemical system for energy recovery and wastewater reclamation

Nicolau, E.; Fonseca, J.; Rodríguez-Martínez, J.; Richardson, Tra-My; Flynn, M.; Griebenow, K.; Cabrera, C.R.

 

  • DOI: 10.1021/sc400342x

Real-Time Detection of Telomerase Activity in Cancer Cells using a Label-Free Electrochemical Impedimetric Biosensing Microchip

Cunci L, Vargas MM, Cunci R, Gomez-Moreno R, Perez I, Baerga-Ortiz A, Gonzalez CI, Cabrera CR. Real-Time Detection of Telomerase Activity in Cancer Cells using a Label-Free Electrochemical Impedimetric Biosensing Microchip.

  • PubMed PMID: 25598969
  • PubMed Central PMCID: PMC4295792.

The role of HuR in the post-transcriptional regulation of interleukin-3 in T cells.

González-Feliciano JA, Hernández-Pérez M, Estrella LA, Colón-López DD, López A, Martínez M, Maurás-Rivera KR, Lasalde C, Martínez D, Araujo-Pérez F, González CI. The role of HuR in the post-transcriptional regulation of interleukin-3 in T cells.

  • PubMed PMID: 24658545
  • PubMed Central PMCID: PMC3962401.

Identification and functional analysis of novel phosphorylation sites in the RNA surveillance protein Upf1

Lasalde C, Rivera AV, León AJ, González-Feliciano JA, Estrella LA, Rodríguez-Cruz EN, Correa ME, Cajigas IJ, Bracho DP, Vega IE, Wilkinson MF, González CI.

Identification and functional analysis of novel phosphorylation sites in the RNA surveillance protein Upf1. Nucleic Acids Res.

  • PubMed PMID: 24198248;
  • PubMed Central PMCID: PMC3919615.

Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles

Castillo B, Bromberg L, López X, Badillo V, González Feliciano JA, González CI, Hatton TA, Barletta G. Intracellular Delivery of siRNA by Polycationic Superparamagnetic Nanoparticles.

  • PubMed PMID: 22970377
  • PubMed Central PMCID: PMC3437298.

Pharmacogenetics of healthy volunteers in Puerto Rico.

Claudio-Campos K, Orengo-Mercado C, Renta JY, Peguero M, García R, Hernández G, Corey S, Cadilla CL, Duconge J. Pharmacogenetics of healthy volunteers in Puerto Rico. Drug Metabol Personal Ther. 2015 Dec 1;30(4):239-49. doi: 10.1515/dmpt-2015-0021.

  • PubMed PMID: 26501165.

Molecular Cloning and Characterization of a (Lys)(6)-Tagged Sulfide-Reactive Hemoglobin I from Lucina pectinata.

Díaz-Ayala R, Moya-Rodríguez A, Pietri R, Cadilla CL, López-Garriga J. Molecular Cloning and Characterization of a (Lys)(6)-Tagged Sulfide-Reactive Hemoglobin I from Lucina pectinata.

  • PubMed PMID: 26482241.

Setleis syndrome: clinical, molecular and structural studies of the first TWIST2 missense mutation.

Rosti RO, Uyguner ZO, Nazarenko I, Bekerecioglu M, Cadilla CL, Ozgur H, Lee BH, Aggarwal AK, Pehlivan S, Desnick RJ. Setleis syndrome: clinical, molecular and structural studies of the first TWIST2 missense mutation.

  • PubMed PMID: 25410422.

Pharmacogenetic association study of warfarin safety endpoints in Puerto Ricans.

Valentín II, Rivera G, Nieves-Plaza M, Cruz I, Renta JY, Cadilla CL, Feliu JF, Seip RL, Ruaño G, Duconge J. Pharmacogenetic association study of warfarin safety endpoints in Puerto Ricans. P R Health Sci J. 2014 Sep;33(3):97-104.

  • PubMed PMID:25244877
  • PubMed Central PMCID: PMC4196861.

CYP2D6’s functional status associated with the length of hospitalization stay in psychiatric patients: a twist in the tale or evidence that matters?

Duconge J, Cadilla CL. CYP2D6’s functional status associated with the length of hospitalization stay in psychiatric patients: a twist in the tale or evidence that matters? Biomark Med. 2013 Dec;7(6):913-4. doi: 10.2217/bmm.13.109.

  • PubMed PMID: 24266824;
  • PubMed Central PMCID: PMC4109677.

Ocular Findings in Patients with the Hermansky-Pudlak Syndrome (Types 1 and 3)

Jardón J, Izquierdo NJ, Renta JY, García-Rodríguez O, Cadilla CL. Ocular Findings in Patients with the Hermansky-Pudlak Syndrome (Types 1 and 3).

  • PubMed PMID: 24766090
  • PubMed Central PMCID: PMC4232478.

Paramagnetic dithiolene complexes as metallo-ligands: ether/thioether coordination

Jeon; S. Calancea;A. Panja; D. Piñero; P. Dechambenoit; C. Coulon; A. Wattiaux; P. Rosa; C. Mathonière; R. Clérac, “Spin crossover or intra-molecular electron transfer in a cyanido-bridged Fe/Co dinuclear dumbbell: a matter of state”, Chem. Sci., 2013, 4, 2463-2470.

Spin crossover or intramolecular electron transfer in a cyanido-bridged Fe/Co dinuclear dumbbell: a matter of state

Jeon; S. Calancea;A. Panja; D. Piñero; P. Dechambenoit; C. Coulon; A. Wattiaux; P. Rosa; C. Mathonière; R. Clérac, “Spin crossover or intra-molecular electron transfer in a cyanido-bridged Fe/Co dinuclear dumbbell: a matter of state”, Chem. Sci., 20134, 2463-2470.

Bioelectrochemistry of non-covalent immobilized alcohol dehydrogenase on oxidized diamond nanoparticles

Nicolau E, Méndez J, Fonseca JJ, Griebenow K, Cabrera CR. Bioelectrochemistry of non-covalent immobilized alcohol dehydrogenase on oxidized diamond nanoparticles.

  • PubMed PMID: 22154812.

Catalytic effect of ultrananocrystalline Fe3O4 on algal bio-crude production via HTL process.

Rojas-Pérez A, Diaz-Diestra D, Frias-Flores CB, Beltran-Huarac J, Das KC, Weiner BR, Morell G, Díaz-Vázquez LM. Catalytic effect of ultrananocrystalline Fe3O4 on algal bio-crude production via HTL process. Nanoscale. 2015 Nov 14;7(42):17664-71. doi: 10.1039/c5nr04404a. Epub 2015 Oct 14.

  • PubMed PMID: 26465090.

Fringe structures and tunable bandgap width of 2D boron nitride nanosheets.

Feng P, Sajjad M, Li EY, Zhang H, Chu J, Aldalbahi A, Morell G. Fringe structures and tunable bandgap width of 2D boron nitride nanosheets. Beilstein J Nanotechnol.

  • PubMed PMID: 25161852
  • PubMed Central PMCID: PMC4142973.

Ultrananocrystalline diamond-decorated silicon nanowire field emitters

Rosti RO, Uyguner ZO, Nazarenko I, Bekerecioglu M, Cadilla CL, Ozgur H, Lee BH, Aggarwal AK, Pehlivan S, Desnick RJ. Setleis syndrome: clinical, molecular and structural studies of the first TWIST2 missense mutation.

  • PubMed PMID: 25410422.

Single-crystal γ-MnS nanowires conformally coated with carbon

Beltran-Huarac J, Resto O, Carpena-Nuñez J, Jadwisienczak WM, Fonseca LF, Weiner BR, Morell G. Single-crystal γ-MnS nanowires conformally coated with carbon. ACS Appl Mater Interfaces. 2014 Jan 22;6(2):1180-6. doi: 10.1021/am404746k. Epub 2014 Jan 10.

  • PubMed PMID: 24392737.

The α7 nicotinic receptor is up-regulated in macrophages from HIV-seropositive women: Consequences to the cholinergic anti-inflammatory response Clinical & Translational Immunology

Delgado-Vélez, M, Baez-Pagan, CA, Gerena, Y, Quesada, O, Santiago-Perez, LI, Capo-Velez, C, Wojna, V, Melendez, L, Leon, R, Lasalde-Dominicci, J. The α7 nicotinic receptor is up-regulated in macrophages from HIV-seropositive women: Consequences to the cholinergic anti-inflammatory response Clinical & Translational Immunology. (2015) Dec 11:4(12):e53 DOI:101038/cti201531

Expression of CHRFAM7A and CHRNA7 in neuronal cells and postmortem brain of HIV-infected patients: considerations for HIV-associated neurocognitive disorder.

Ramos FM, Delgado-Vélez M, Ortiz ÁL, Báez-Pagán CA, Quesada O, Lasalde-Dominicci JA. Expression of CHRFAM7A and CHRNA7 in neuronal cells and postmortem brain of HIV-infected patients: considerations for HIV-associated neurocognitive disorder. J Neurovirol. 2015 Nov 13. [Epub ahead of print]

  • PubMed PMID: 26567012.

Decreased glial and synaptic glutamate uptake in the striatum of HIV-1 gp120 transgenic mice.

Melendez RI, Roman C, Capo-Velez CM, Lasalde-Dominicci JA. Decreased glial and synaptic glutamate uptake in the striatum of HIV-1 gp120 transgenic mice. J Neurovirol. 2015 Nov 13. [Epub ahead of print]

  • PubMed PMID: 26567011.

Assessment of the functionality and stability of detergent purified nAChR from Torpedo using lipidic matrixes and macroscopic electrophysiology.

Padilla-Morales LF, Colón-Sáez JO, González-Nieves JE, Quesada-González O, Lasalde-Dominicci JA. Assessment of the functionality and stability of detergent purified nAChR from Torpedo using lipidic matrixes and macroscopic electrophysiology. Biochim Biophys Acta. 2016 Jan;1858(1):47-56. doi:10.1016/j.bbamem.2015.10.002. Epub 2015 Oct 8.

  • PubMed PMID: 26454038.

Lateral Diffusion, Function, and Expression of the Slow Channel Congenital Myasthenia Syndrome αC418W Nicotinic Receptor Mutation with Changes in Lipid Raft Components.

Oyola-Cintrón J, Caballero-Rivera D, Ballester L, Baéz-Pagán CA, Martínez HL, Vélez-Arroyo KP, Quesada O, Lasalde-Dominicci JA. Lateral Diffusion, Function, and Expression of the Slow Channel Congenital Myasthenia Syndrome αC418W Nicotinic Receptor Mutation with Changes in Lipid Raft Components. J Biol Chem.2015 Oct 30;290(44):26790-800. doi: 10.1074/jbc.M115.678573. Epub 2015 Sep 9. PubMed PMID: 26354438;

  • PubMed Central PMCID: PMC4646332.

Engineering α4β2 nAChRs with reduced or increased nicotine sensitivity via selective disruption of consensus sites in the M3-M4 cytoplasmic loop of the α4 subunit.

Biaggi-Labiosa NM, Avilés-Pagán E, Caballero-Rivera D, Báez-Pagán CA, Lasalde-Dominicci JA. Engineering α4β2 nAChRs with reduced or increased nicotine sensitivity via selective disruption of consensus sites in the M3-M4 cytoplasmic loop of the α4 subunit. Neuropharmacology. 2015 Dec;99:273-84. doi:10.1016/j.neuropharm.2015.04.022. Epub 2015 May 6.

  • PubMed PMID: 25957813
  • PubMed Central PMCID: PMC4636472.

Activation of the Macrophage α7 Nicotinic Acetylcholine Receptor and Control of Inflammation.

Báez-Pagán CA, Delgado-Vélez M, Lasalde-Dominicci JA. Activation of the Macrophage α7 Nicotinic Acetylcholine Receptor and Control of Inflammation. J Neuroimmune Pharmacol. 2015 Sep;10(3):468-76. doi: 10.1007/s11481-015-9601-5. Epub 2015 Apr 14.

  • PubMed PMID: 25870122
  • PubMed Central PMCID: PMC4546521.

Fluoxetine is neuroprotective in slow-channel congenital myasthenic syndrome.

Zhu H, Grajales-Reyes GE, Alicea-Vázquez V, Grajales-Reyes JG, Robinson K, Pytel P, Báez-Pagán CA, Lasalde-Dominicci JA, Gomez CM. Fluoxetine is neuroprotective in slow-channel congenital myasthenic syndrome. Exp Neurol. 2015 Aug;270:88-94. doi: 10.1016/j.expneurol.2014.10.008. Epub 2014 Oct 23.

  • PubMed PMID: 25448156
  • PubMed Central PMCID: PMC4430442.

Transgenic mouse model reveals an unsuspected role of the acetylcholine receptor in statin-induced neuromuscular adverse drug reactions.

Grajales-Reyes GE, Báez-Pagán CA, Zhu H, Grajales-Reyes JG, Delgado-Vélez M, García-Beltrán WF, Luciano CA, Quesada O, Ramírez R, Gómez CM, Lasalde-Dominicci JA. Transgenic mouse model reveals an unsuspected role of the acetylcholine receptor in statin-induced neuromuscular adverse drug reactions. Pharmacogenomics J. 2013 Aug;13(4):362-8. doi: 10.1038/tpj.2012.21. Epub 2012 Jun 12.

  • PubMed PMID: 22688219
  • PubMed Central PMCID: PMC3972001.

Tryptophan scanning mutagenesis reveals distortions in the helical structure of the δM4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor.

Caballero-Rivera D, Cruz-Nieves OA, Oyola-Cintrón J, Torres-Nunez DA, Otero-Cruz JD, Lasalde-Dominicci JA. Tryptophan scanning mutagenesis reveals distortions in the helical structure of the δM4 transmembrane domain of the Torpedo californica nicotinic acetylcholine receptor. Channels (Austin). 2012 Mar-Apr;6(2):111-23. doi: 10.4161/chan.19540. Epub 2012 Mar 1.

  • PubMed PMID: 22622285
  • PubMed Central PMCID: PMC3396688.

SorLA in glia: shared subcellular distribution patterns with caveolin-1.

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