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Capabilities and Expertise
and control of polymorphs, solvates, and salts formation in manufacturing processes including online characterization
solution and melt crystallization processes
(variable temperature) on crystalline compounds (polymorphs, salts, co-crystals, solvates, etc.) for phase identification and elucidation of the kinetics for phase transformation
methods (powder, thin Oilm, variable temperature and pressure, single crystal) for phase identiOication, determination of strain and particle size, phase transformation kinetics, unit cell indexing, and crystal structure elucidation
to determine melting points, enthalpies, (phase or glass) transition temperatures, heat capacities of solid materials
of structured particulate systems for tailored and personalized medication including micro- and nanoparticles
of integrated continuous pharmaceutical manufacturing including puriOication, separation, and formulation
to aid the transformation into advanced manufacturing
We focus on solid state characterization of materials to offer unparalleled technical expertise and deliver solutions to your most critical problems in product development and process design.
Solid Form Discovery
Screening for new solid forms of existing materials offers potential to tune properties (solubility, color, conductivity, stability, etc.) without the need for additional synthesis. Our polymorph screening services serve to assess the propensity of a material to exhibit this phenomena and provide expertise to promote or inhibit the appearance of polymorphs during a crystallization process including in situ monitoring (PATs) and characterization.
Crystallization Process Design
Process development/optimization to manufacture crystalline materials with tailored properties including polymorph, crystal size, and purity.